The Plastic Exposure Reduction Transforms Health
The PERTH Trial
Are you curious about your exposure to plastic chemicals?
Researchers from The University of Western Australia are investigating our exposure to plastic chemicals and whether reducing exposure to plastics could transform our health.
- Do we know if plastic chemicals are a threat to human health?
Rising rates of obesity, heart disease, type 2 diabetes and other chronic conditions coincide with increasing use of plastic-associated chemicals like BPA and phthalates in our environment and everyday lives.
These chemicals are considered hazardous because they disrupt our hormone system and so are called ‘endocrine disrupters’ but research in this field is limited.
- We need high quality research in Australia!
Firstly, we need to find the common sources of exposure to plastic chemicals in Western Australia, and examine how much of these chemicals we consume, process, and eventually excrete from our bodies.
Once we understand how much we are exposed to, the next step is to avoid the known sources of these plastic chemicals and see if there is a reduction of plastic chemicals in our urine and stool.
Finally, blood tests taken during the study will help identify any markers of inflammation associated with plastic chemicals that can cause chronic diseases.
To detect the levels of plastic chemicals in the body
To identify possible sources of exposure to plastic chemicals in the Perth population
To investigate if reducing exposure to plastic chemicals results in decreased excretion from the body
Frequently asked questions
- Am I eligible to participate in the trial?
If you are aged between 18 and 60 years old and live in the Perth Metropolitan area you may be eligible. We encourage you to complete the expression of interest form by clicking on the link above. An email will then be sent to you to complete a few pre-screening questions to confirm your suitability for health screening followed by the study information sheet.
- If I participate in the trial, what activities will I be involved in?
- You will attend two appointments lasting about 2 hours at the Harry Perkins Institute on the QEII Campus over a period of one week.
- At the first appointment, the study doctor will discuss what the study involves, obtain your consent to participate in the study, and proceed with a thorough health check-up.
- The next morning, at your local Clinipath pathology clinic, you will have a fasting blood test to check your general health.
- The next day we will phone you with the results and confirm your second appointment.
- The day before your second appointment we will ask you to self-collect a urine and stool sample, and a nasal rinse.
- At the second appointment, you will have another blood test, complete some questionnaires, and participate in an interview with a qualified dietitian.
- On the Sunday following your second appointment, you will self-collect another urine and stool sample, and a nasal rinse.
- The next day, Monday you will have a telephone appointment with the study dietitian.
- Within 2 weeks we will send you a participant satisfaction survey to complete.
- What are the study assessments?
On-line questionnaires will ask you about potential exposure to plastic chemicals through diet, lifestyle, and occupation.
A qualified dietitian will interview you about your diet and food preparation practices.
You will be asked to self-collect urine, stool, and nasal washing samples at home using the kits we provide you.
- Will I have access to my individual results?
We will provide you with a hard copy of results of your health screening blood tests at your second visit.
You will not receive results of the research tests individually because it is not known what the clinical importance of the results are to individuals until they have been analysed within a larger group of people.
The results of the study will be in the public domain and information on how to access the reports and manuscripts will be posted on the study website.
- How do I get to my booked clinic appointment?
We are located at the Harry Perkins Institute of Medical Research on the QEII Campus at 6 Verdun Street, Nedlands WA 6009. There is paid public parking available on site and the Institute is easy to get to with public transport.
- I don’t live within the Perth Metro region, am I still able to participate?
At this stage, the study is confined to the Metropolitan area and surrounds.
- Who is funding the trial?
The Minderoo Foundation has awarded a research grant to the University of Western Australia.
Find out more about the Foundation's Plastics initiative and human health focus.
- Is there any reimbursement for my time and travel costs?
You will be given $20.00 for parking expenses and a $50.00 gift voucher.
- How long does the trial last?
Your participation in the trial will be over a period of two weeks.
- Further reading
To learn more about the PERTH Trial, email us at [email protected] or contact a member of the clinical research team:
- Sharon (Clinical Trial Coordinator)
- M: 0403 262 229
- Claire (Dietetics Research Officer)
- M: 0403 262 214
- Andrea (Dietetics Research Officer)
- M: 0403 262 306
We are located at the Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands WA 6009
- Parking information
- Travel and Parking Instructions [PDF, 197KB]
The University of Western Australia Human Research Ethics Committee has approved this study (Approval ID: 2021/ET001118)
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