Biochemistry and molecular genetics
A leading destination for research and study
Biochemistry and molecular genetics are revolutionising our understanding of the mechanisms of life. At UWA, innovative research and strong industry collaboration is enabling us to create new therapeutics and biotechnological tools, transforming medicine, improving agriculture and advancing our understanding of evolutionary biology. Researchers in the School engage in readily translatable, interdisciplinary research in a variety of fields including structural biology, metabolomics, proteomics, redox regulation and signalling, RNA biology, genomics and epigenomics, synthetic biology, plant genetics, organelle biogenesis, chemical biology, drug design, bionanotechnology, enzymology and computational biology.
part of the School of Molecular Sciences, our scientists work closely with other
schools, research centres and faculties within the University and across
the world to answer complex biological and chemical problems, allowing UWA to provide a vibrant, international environment with
far-reaching research potential.
The Bayliss Building offers cutting-edge facilities for biomolecular analysis and makes the School as a leading destination for research and study.
View the full list of Biochemistry and Molecular Genetics staff in our Contact Directory.
Secondary metabolite biosynthesis
This UWA research project uses functional genomics to identify gene clusters in the fungal pathogens that may encode secondary metabolites.
Which cellular cues regulate seasonal perception and shoot growth
This project will investigate the convergence of oxygen, redox and energy cues in regulating the cell cycle in plant meristems. Studies can span several domains, from the apical meristem of Arabidopsis or tomato, to the axillary quiescent or dormant buds of perennial species. Approaches will be based on molecular physiology, including use of mutant lines and potentially genetic manipulation.
Applications of NanoSIMS analysis on biological studies
This UWA research project will develop imaging techniques using novel methodology and biological applications with the state-of-the-art SIMS lab in UWA.
Exploiting chemical signals to boost plant performance
Understanding how plants perceive and respond to changes in their environment is fundamental to improving the performance of crops in the field. This UWA project aims to define the function of the karrikin signalling pathway in plant physiology and establish how it interacts with that of other plant hormones.
Deciphering chemical signaling processes during plant development
This UWA research project investigates how plants use chemical signals to control their growth and development in response to different environments.
Probing the roles bacteria play in infant health
This research project investigates the glycoconjugates found in human milk and the role how these bacteria are beneficial to infant health.
A translational approach to determine how is our immune health under breastfeeding influence
This research project investigates how breastmilk affects our immune health.
Smoke alarm: Discovering new signalling compounds that operate in plants
The aims of this UWA research project are to investigate diverse sources of biological material for karrikin-like activity using existing bioassays and develop new bioassays, and characterise them with karrikins to determine their performance.
Tackling carbohydrate processing enzymes head on
This research project investigates the role of carbohydrate-processing enzymes implicated in human disease, antibiotic resistance and digestion.
Discovering how respiration affects plant development
This research project uses knockout and overexpressing lines of plant specific complex II subunits to characterise their functions.
What are the wheat proteins that define wheat quality, enable disease resistance and tolerate harsh environmental conditions?
This UWA research project will assess metabolic pathway expression in wheat tissues to develop protein markers for industry.
Understanding how salinity damages wheat and barley crops
This research project will build a more complete picture of global protein expression changes in salt-stressed wheat or barley seedling roots.
Unique components of human milk
This research project will develop analytical methodologies to analyse components of human milk and advance the accuracy of human milk analysis.
Genome mining of virulent small molecules in human fungal pathogens
Using the synthetic biology platforms available in the lab, this UWA research project uses functional genomics to discover new strategies for novel diagnostics and therapeutics.
Protein turnover to measure the role of degradation in the costs of cell function and the acclimation of plants to environments
This research project considers which protein features are responsible for degradation rates and builds evidence for changing protein turnover.
Synthetic biology tools for biosynthesis
This UWA research project investigates novel molecules from sequenced fungal genomes for application in medicine and agriculture.
Collaborations and research partners
Our industry partners include:
Centres and groups
We work with leading researchers from nationally recognised organisations.
School of Molecular Sciences
The School of Molecular Science’s innovative teaching and research applies chemical science to generate practical solutions to real-world problems.
The Chemistry research group focuses on the synthesis and study of molecules, from the simplest diatomics to polymers and biological machines, and their interactions.
Furthering human knowledge and serving humanity
Our research is redefining the boundaries of scientific knowledge and driving positive global change for better lives and communities.
Optimising physical and mental performance
Our researchers are discovering ways to improve the quality of life by better understanding how we think, feel and move.