Tracking evolution and biosynthesis of cyclic peptide natural products
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Proteins date back to the time of sabre toothed cats
Plant scientists at The University of Western Australia have discovered a completely new family of small proteins called PLPs (PawL Peptides) that form by piggybacking on other proteins. The scientists found ‘protein-piggybacking’ of PLPs began in seeds of a daisy ancestor that existed 45 million years ago during the Eocene Epoch period - around the time sabre toothed cats walked the earth.Read more
Proteins hiding in proteins take an evolutionary shortcut
How a drug-like protein ring evolved in sunflowers has been pieced together by Australian and US scientists in a study published in Molecular Biology and Evolution. Although the evolutionary process took some 45 million years, the researchers are still calling it a shortcut. The study team included researchers from The University of Western Australia; La Trobe University in Melbourne, the University of Tennessee and the University of Texas.Read more