Applications of NanoSIMS analysis on biological studies

Developing novel methodology and biological applications using advanced imaging techniques

Developments of imaging techniques have enabled numerous important discoveries. The NanoSIMS (Nanoscale Secondary Ion Mass Spectrometry), as a type of imaging mass spectrometry, is a relatively new technique for biological imaging. The characteristics of the NanoSIMS achieving high spatial resolution, high mass resolution and high sensitivity make it powerful to track molecules and quantify biological processes in subcellular level.

This project is to develop novel methodology and biological applications with the state-of-the-art SIMS lab in UWA.

There are many directions this project can take, including the development of multimodal and multiscale bioimaging platform based on complementary techniques, as well as understanding of biological processes, such as molecular mechanisms of lipid transport; action mechanisms of pharmaceutical compounds; and toxicology of nanomaterials.

This is an interdisciplinary project working closely with collaborators. There are opportunities working with international research institutes (UCLA, Oxford University) and industry partners.

Suggested readings

Research team leader: Dr Haibo Jiang

I am currently a lecturer at The University of Western Australia. Before my relocation to Australia in 2015, I was a graduate student and a postdoctoral research fellow at Materials Department at University of Oxford (2010-2015). My research efforts have focused largely on development of novel imaging methodologies and the use of new technologies to decipher mechanisms for lipid metabolism in health, particularly in the setting of cardiovascular diseases.

How to apply

Interested in becoming part of this project? Complete the following steps to submit your expression of interest:

Step 1 - Check criteria

General UWA PhD entrance requirements can be found on the Future Students website.

This is an interdisciplinary project, and it suits students with background in cell biology, biochemistry, chemistry or materials science. Experience on tissue culture is desirable, but not essential.

Step 2 - Submit enquiry to research team leader

Step 3 - Lodge application

After you have discussed your project with the research team leader, you should be in a position to proceed to the next step of the UWA application process: Lodge an application. Different application procedures apply to domestic and international students.


Domestic students

All domestic students may apply for Research Training Program and University Postgraduate Awards (UPA) scholarships.

The Australian Government's Endeavour Awards and Scholarships are available to Australian applicants for study in participating countries and regions.

International students

A range of scholarships are available from international organisations and governments. The full list, organised by country, is available on the Future Students website.

In addition, all international students may apply for International Research Training Program scholarships.

The Australian Government's Endeavour Awards and Scholarships are available to international applicants from participating countries and regions.

Indigenous students
Indigenous students are encouraged to apply for Indigenous Postgraduate Research Supplementary Scholarships.
Forrest Foundation scholarships
All international and Australian students who wish to study towards the degree of Doctor of Philosophy (PhD) at The University of Western Australia may apply for Forrest Scholarships.

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