The University of Western Australia
Dr Kimberley Strong
Contact details
| Address | School of Pathology and Laboratory Medicine The University of Western Australia (M504) 35 Stirling Highway CRAWLEY WA 6009 Australia |
|---|---|
| Phone | 9346 2076 |
| Fax | 9346 2891 |
| kimberley.strong@uwa.edu.au |
Key research
- Albuminuria assays are not all created equal
- Albuminuria (high levels of albumin in urine) has long been recognised as a marker of disease, so cheap and convenient methods of measuring albumin have been made available. Unfortunately, these assays detect only a small proportion of the albumin present in urine (<10%) and as a consequence they can return false negative results.
- Our research team uses a multi-faceted approach to measure all forms of urinary albumin, including modified albumin and albumin breakdown products. These products, largely ignored by albuminuria scientists and clinicians, pose exciting new research possibilities: yielding insights into pathologic processes, leading to development of new and improved assays for albuminuria and enabling earlier detection of disease.
- Patient samples
- We maintain a large collection of urine samples collected from patients on the day of admission to ICU, matched with comprehensive clinical data that extends beyond patient recovery and discharge. These samples can be made available for research collaborations or industrial partners wanting to develop improved urinary assays for diagnostic or prognostic purposes in ICU.
- Experimental models
- We utilise a variety of experimental models in mice and rats, specialising in diseases of the kidney. We adhere to the principles of Replacement, Reduction and Refinement and are keen to share tissues or collaborate on projects in diabetes, glomerulonephritis, toxic nephrosis, hypoalbuminaemia and sepsis.
Major research interests
- Diagnosis of renal disease
- Proteinuria/albuminuria
- Proteomics
- Endocrinology
- Medical biochemistry and clinical urology
- Nephrology and urology
Qualifications
BSc PhD Monash
Teaching
Current co-ordinator of the following units:
PATH3301 / PATH3351
PATH3302 / PATH3352 & IMED3310
Teaching in:
PATH2201
IMED3342
PATH3301 / PATH3351
PATH3302 / PATH3352 & IMED3310
Teaching in:
PATH2201
IMED3342
Current projects
- Immuno-nonreactive albumin as a biomarker in critically ill patients.
- Hypoalbuminaemia in experimental sepsis.
- Large albumin fragments in urine.
- Albumin concentration in stored urine samples.
Research profile
