The University of Western Australia
Dr Gavin Pinniger
Lecturer
Contact details
| Address | Physiology The University of Western Australia (M311) 35 Stirling Highway CRAWLEY WA 6009 Australia |
|---|---|
| Phone | 6488 3380 |
| Fax | 6488 1025 |
| gavin.pinniger@uwa.edu.au |
Location
Room 1.10A, Physiology Building, Crawley campus
Biography
Dr Gavin Pinniger completed his undergraduate and PhD studies in the Department of Biomedical Science at the University of Wollongong in New South Wales. He then received a Travelling Research Fellowship from The Wellcome Trust to conduct his post-doctoral research at the University of Bristol in the United Kingdom before coming to UWA.
Key research
- Dr Pinniger's research deals with the physiology of skeletal muscle. He is particularly interested in the molecular mechanisms underlying muscle contraction and the evaluation of medical treatments for muscular diseases, such as Duchenne muscular dystrophy.
Major research interests
- Neuromuscular control
- Skeletal muscle physiology
Qualifications
BSc PhD W'gong
Publications
Ridgley, J.A., Pinniger, G.J., Hamer, P.W. & Grounds, M.D. (2009) The physiological effects of IGF-1 (class 1:Ea transgene) over-expression on exercise-induced muscle damage and adaptation in dystrophic muscles of mdx mice. Pflugers Archive – European Journal of Physiology. 457:1121–1132.
Palmisano, S., Pinniger, G.J., Ash, A., & Steele, J.R. (2009). Effects of simulated viewpoint jitter on visually induced postural sway. Perception, 38:442-53..
Ranatunga, K.W., Coupland, M.E., Pinniger, G.J., Roots, H. & Offer, G.W. (2007). Force generation examined by laser temperature-jumps in shortening and lengthening mammalian (rabbit psoas) muscle fibres. Journal of Physiology. 585(1):263-77.
Pinniger, G.J. & Cresswell, A.G. (2007). Residual force enhancement after lengthening is present during submaximal plantar flexion and dorsiflexion actions in humans. Journal of Applied Physiology, 102(1):18-25.
Pinniger, G.J., Ranatunga, K.W., & Offer, G.W. (2006). Crossbridge and non-crossbridge contributions to tension in lengthening muscle: force-induced reversal of the power stroke. Journal of Physiology. 573(3):627-643.
Bruton, J.D., Pinniger, G.J., Lännergren, J. & Westerblad, H. (2006). The effects of the myosin-II inhibitor N-benzyl-p-toluene sulphonamide (BTS) on fatigue in mouse single intact toe muscle fibres. Acta Physiologica Scandinavica, 186:59-66.
Pinniger, G.J., Bruton, J.D., Westerblad, H. & Ranatunga, K.W. (2005). Effects of a myosin-II inhibitor (N-benzyl-p-toluene sulphonamide, BTS) on contractile characteristics of intact fast-twitch mammalian muscle fibres. Journal of Muscle Research and Cell Motility, 26:135-141.
Coupland, M.E., Pinniger, G.J. & Ranatunga, K.W. (2005). Endothermic force generation, temperature-jump experiments and effects of increased [MgADP] in rabbit psoas muscle fibres. Journal of Physiology, 567(2):471-492.
Coupland, M.E., Pinniger, G.J. & Ranatunga, K.W. (2005). Tension responses to rapid (laser) temperature-jumps during twitch contractions in intact rat muscle fibres. Journal of Muscle Research and Cell Motility, 26:113-122.
Pinniger, G.J., Steele, J.R. & Cresswell, A.G. (2003). The force-velocity relationship of the human soleus muscle during submaximal voluntary lengthening actions. European Journal of Applied Physiology, 90(1-2):191-198.
Pinniger, G.J., Nordlund, M.M., Steele, J.R. & Cresswell, A.G. (2001). H-reflex modulation during lengthening and shortening actions of the human triceps surae. Journal of Physiology, 534(3):913-923.
Pinniger, G.J., Steele, J.R., Thorstensson, A., & Cresswell, A.G. (2000). Tension regulation during lengthening and shortening actions of the human soleus muscle. European Journal of Applied Physiology, 81(5):375-83.
Pinniger, G.J., Steele, J.R., & Groeller, H. (2000). Does fatigue induced by repeated dynamic efforts affect hamstring muscle function? Medicine and Science in Sports and Exercise 32(3):647-53.
Palmisano, S., Pinniger, G.J., Ash, A., & Steele, J.R. (2009). Effects of simulated viewpoint jitter on visually induced postural sway. Perception, 38:442-53..
Ranatunga, K.W., Coupland, M.E., Pinniger, G.J., Roots, H. & Offer, G.W. (2007). Force generation examined by laser temperature-jumps in shortening and lengthening mammalian (rabbit psoas) muscle fibres. Journal of Physiology. 585(1):263-77.
Pinniger, G.J. & Cresswell, A.G. (2007). Residual force enhancement after lengthening is present during submaximal plantar flexion and dorsiflexion actions in humans. Journal of Applied Physiology, 102(1):18-25.
Pinniger, G.J., Ranatunga, K.W., & Offer, G.W. (2006). Crossbridge and non-crossbridge contributions to tension in lengthening muscle: force-induced reversal of the power stroke. Journal of Physiology. 573(3):627-643.
Bruton, J.D., Pinniger, G.J., Lännergren, J. & Westerblad, H. (2006). The effects of the myosin-II inhibitor N-benzyl-p-toluene sulphonamide (BTS) on fatigue in mouse single intact toe muscle fibres. Acta Physiologica Scandinavica, 186:59-66.
Pinniger, G.J., Bruton, J.D., Westerblad, H. & Ranatunga, K.W. (2005). Effects of a myosin-II inhibitor (N-benzyl-p-toluene sulphonamide, BTS) on contractile characteristics of intact fast-twitch mammalian muscle fibres. Journal of Muscle Research and Cell Motility, 26:135-141.
Coupland, M.E., Pinniger, G.J. & Ranatunga, K.W. (2005). Endothermic force generation, temperature-jump experiments and effects of increased [MgADP] in rabbit psoas muscle fibres. Journal of Physiology, 567(2):471-492.
Coupland, M.E., Pinniger, G.J. & Ranatunga, K.W. (2005). Tension responses to rapid (laser) temperature-jumps during twitch contractions in intact rat muscle fibres. Journal of Muscle Research and Cell Motility, 26:113-122.
Pinniger, G.J., Steele, J.R. & Cresswell, A.G. (2003). The force-velocity relationship of the human soleus muscle during submaximal voluntary lengthening actions. European Journal of Applied Physiology, 90(1-2):191-198.
Pinniger, G.J., Nordlund, M.M., Steele, J.R. & Cresswell, A.G. (2001). H-reflex modulation during lengthening and shortening actions of the human triceps surae. Journal of Physiology, 534(3):913-923.
Pinniger, G.J., Steele, J.R., Thorstensson, A., & Cresswell, A.G. (2000). Tension regulation during lengthening and shortening actions of the human soleus muscle. European Journal of Applied Physiology, 81(5):375-83.
Pinniger, G.J., Steele, J.R., & Groeller, H. (2000). Does fatigue induced by repeated dynamic efforts affect hamstring muscle function? Medicine and Science in Sports and Exercise 32(3):647-53.
Funding received
Raine Priming Grant
UWA Research Grant
NHMRC Equipment Grant
UWA Research Grant
NHMRC Equipment Grant
Honours and awards
New Investigator Award in Clinical Science
Guest Research Scholarship for the Swedish Institute
NSW Sporting Injuries Committee Best New Research Talent in Science and Medicine in Sport
Guest Research Scholarship for the Swedish Institute
NSW Sporting Injuries Committee Best New Research Talent in Science and Medicine in Sport
Teaching
Dr Pinniger is the Physiology Honours coordinator and course coordinator for IDNT/PODI-1134 Introduction to Normal Systems and also lectures in the following courses:
Graduate Entry Medical Program (GEMP)
PHYL3350 Physiological Control Mechanisms
PHYL2260 Physiology of Adaption and Stress
IMED2201 Normal Systems
IMED2202 Normal Systems
Graduate Entry Medical Program (GEMP)
PHYL3350 Physiological Control Mechanisms
PHYL2260 Physiology of Adaption and Stress
IMED2201 Normal Systems
IMED2202 Normal Systems
Current projects
•Skeletal muscle physiology - molecular mechanisms of stretch-induced force enhancement and adaptation to exercise-induced muscle damage;
•Physiological evaluation of therapeutic and genetic treatments for muscular dystrophy;
•The role of inflammatory cytokines in muscle weakness associated with injury, ageing and disease;
•The susceptibility to ventilator-induced diaphragm dysfunction in the pre-term lamb.
Collaborators
Dr Anthony Bakker, Physiology, UWA
Prof. Miranda Grounds, School of Anatomy and Human Biology, UWA
Prof. Steve Wilton & Dr Sue Fletcher, Australian Neuromuscular Research Institute (ANRI)
Dr Jane Pillow, School of Women and Infant Health, UWA
Prof. Graham Lamb, La Trobe University, Victoria.
•Physiological evaluation of therapeutic and genetic treatments for muscular dystrophy;
•The role of inflammatory cytokines in muscle weakness associated with injury, ageing and disease;
•The susceptibility to ventilator-induced diaphragm dysfunction in the pre-term lamb.
Collaborators
Dr Anthony Bakker, Physiology, UWA
Prof. Miranda Grounds, School of Anatomy and Human Biology, UWA
Prof. Steve Wilton & Dr Sue Fletcher, Australian Neuromuscular Research Institute (ANRI)
Dr Jane Pillow, School of Women and Infant Health, UWA
Prof. Graham Lamb, La Trobe University, Victoria.
Research profile
